Changes in blood coagulation-related parameters in phenobarbital-treated rabbits

Changes in blood coagulation-related parameters in phenobarbital-treated rabbits.

The effects of repeated administration of phenobarbital (PB) on blood coagulation time were examined using male Japanese white SPF rabbits, which are widely used for toxicological studies. PB was administered to the rabbits by oral gavage for 2 weeks, at dose levels of 0, 12.5, 25 and 50 mg/kg/day. Blood was collected on Days 8 and 14 after each day's dosing to perform blood coagulation examina...

Phenobarbital < PB ) - in related parameters in duced changes in blood coagulation - pregnant rats , lactating rats and pups

Effects of repeated administration ofphenobarbital (PB) on blood coagulation-related parameters were examined in non-pregnant, pregnant and lactating rats, and also in pups born to PB-treated lactating dams. PB was orally administered at a dose level of 80 mglkglday to pregnant (from gestation day (GD) 13), postpartum (from postpartum day (PPD) 7) and non-pregnant rats (from 13 weeks of age) fo...

Blood coagulation - related parameter changes in Dawley ( SD ) rats treated with phenobarbital ( PB ) plus vitamin K Sprague - and PB

Effects ofdose and duration ofphenobarbital (PB) administration and those ofco-administration of PB and vitamin K on blood coagulation-related parameters were examined in specific pathogen-free (SPF) rats of Sprague-Dawley strain kept on an ordinary diet. In Experiment 1, oral administration of PB (O, 25, 50, 100 or 150 mglkg/day) fbr 2 wecks induccd increases in hcpatic ytochrome P450 content ...

Changes in blood coagulation.

Age-related Changes in some Blood Parameters of Ostrich (Short Communication)

The aim of this study was investigating some blood parameters of blue-neck male ostriches (Struthio camelus) with 4 months old after feeding a diet containing 3% sunflower oil for two months. In the morning, after about 12 h of fasting, some blood samples were collected from the wing vein of ostriches at the beginning and 60 days of study in department of animal sceince Arak university . The pl...